GET https://rct.dev.bbntimes.com/science/covid-vaccines-and-the-nature-of-engineering

Response
200 OK
IP
52.14.183.78
Profiled on
Token
157e9a

ArticleController :: show

Request

GET Parameters

None

POST Parameters

None

Uploaded Files

None

Request Attributes

Key Value
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"App\Controller\ArticleController::show"
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_stopwatch_token 
"801b9a"
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"science"
slug 
"covid-vaccines-and-the-nature-of-engineering"

Request Headers

Header Value
accept 
"*/*"
accept-encoding 
"gzip, br, zstd, deflate"
connection 
"close"
cookie 
"PHPSESSID=bgc0b7h748s5le9r2b3ihf0vqm; laikanxia_cookie_id=250222164817691; care_did=7c2e799a-56bb-4d46-ae3b-24752d8492ea; laikanxia_google_v=1"
host 
"rct.dev.bbntimes.com"
user-agent 
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
x-php-ob-level 
"1"

Request Content

Request content not available (it was retrieved as a resource).

Response

Response Headers

Header Value
cache-control 
"no-cache, private"
content-type 
"text/html; charset=UTF-8"
date 
"Sat, 22 Feb 2025 08:48:35 GMT"
link 
"</build/runtime.js>; rel="preload"; as="script",</build/644.js>; rel="preload"; as="script",</build/502.js>; rel="preload"; as="script",</build/app.js>; rel="preload"; as="script",</build/view-more.js>; rel="preload"; as="script",</build/term-condition.js>; rel="preload"; as="script",</build/contact.js>; rel="preload"; as="script",</build/scroll-infinite-article.js>; rel="preload"; as="script",</build/app.css>; rel="preload"; as="style",</build/cookie-style.css>; rel="preload"; as="style",</build/term-condition-css.css>; rel="preload"; as="style",</build/contact-css.css>; rel="preload"; as="style",</build/comment-css.css>; rel="preload"; as="style""
x-debug-token 
"157e9a"

Cookies

Request Cookies

Key Value
PHPSESSID 
"bgc0b7h748s5le9r2b3ihf0vqm"
care_did 
"7c2e799a-56bb-4d46-ae3b-24752d8492ea"
laikanxia_cookie_id 
"250222164817691"
laikanxia_google_v 
"1"

Response Cookies

No response cookies

Session 6

Session Metadata

Key Value
Created 
"Sat, 22 Feb 25 08:48:19 +0000"
Last used 
"Sat, 22 Feb 25 08:48:34 +0000"
Lifetime 
0

Session Attributes

Attribute Value
_csrf/https-comment 
"qJHE4etMZt0VT0IxuZgzZERJUCC33LvNrhqj0Rtt0ts"
_csrf/https-cookie_accept 
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Session Usage

6 Usages
Stateless check enabled
Usage
Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:76
Show trace 
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:79
Show trace 
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:52
Show trace 
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:56
Show trace 
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    "line" => 220
    "function" => "createView"
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    "function" => "run"
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    ]
    "function" => "require_once"
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]
Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage:41
Show trace 
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-core/Authentication/Token/Storage/UsageTrackingTokenStorage.php"
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    "function" => "getMetadataBag"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
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]
Symfony\Component\Security\Http\Firewall\ContextListener:171
Show trace 
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-http/Firewall/ContextListener.php"
    "line" => 171
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Flashes

Flashes

No flash messages were created.

Server Parameters

Server Parameters

Defined in .env

Key Value
APP_ENV 
"dev"
APP_SECRET 
"0a988e63f011514eaabfc650b599af4d"
CORS_ALLOW_ORIGIN 
"*"
DATABASE_URL 
"mysql://bbndb_rctuser:33F5W25z40or0f7@localhost:3306/rct_bbntimes"
GOOGLE_RECAPTCHA_SECRET_KEY 
"6LdV5fgpAAAAANxzTG8ZMfIjil1wu-1vrQvnUt-x"
GOOGLE_RECAPTCHA_SITE_KEY 
"6LdV5fgpAAAAAENKcn73MJAhQrbtQeqgyC4wDLMP"
MAILER_DSN 
"smtp://no-reply%40rct.dev.bbntimes.com:Bl6%26gLD48%26Of919@rct.dev.bbntimes.com:465"
MARIADB_PASSWORD 
"i!87pK&!85ezc8"

Defined as regular env variables

Key Value
APP_DEBUG 
"1"
BASE 
"/public"
CONTEXT_DOCUMENT_ROOT 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
CONTEXT_PREFIX 
""
DOCUMENT_ROOT 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
FCGI_ROLE 
"RESPONDER"
GATEWAY_INTERFACE 
"CGI/1.1"
HTTPS 
"on"
HTTP_ACCEPT 
"*/*"
HTTP_ACCEPT_ENCODING 
"gzip, br, zstd, deflate"
HTTP_CONNECTION 
"close"
HTTP_COOKIE 
"PHPSESSID=bgc0b7h748s5le9r2b3ihf0vqm; laikanxia_cookie_id=250222164817691; care_did=7c2e799a-56bb-4d46-ae3b-24752d8492ea; laikanxia_google_v=1"
HTTP_HOST 
"rct.dev.bbntimes.com"
HTTP_USER_AGENT 
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
PATH 
"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/sbin:/bin:/snap/bin"
PHP_SELF 
"/public/index.php"
PP_CUSTOM_PHP_CGI_INDEX 
"plesk-php81-fastcgi"
PP_CUSTOM_PHP_INI 
"/var/www/vhosts/system/rct.dev.bbntimes.com/etc/php.ini"
QUERY_STRING 
""
REDIRECT_BASE 
"/public"
REDIRECT_HTTPS 
"on"
REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_HTTPS 
"on"
REDIRECT_REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/covid-vaccines-and-the-nature-of-engineering"
REDIRECT_REDIRECT_SCRIPT_URL 
"/science/covid-vaccines-and-the-nature-of-engineering"
REDIRECT_REDIRECT_SSL_TLS_SNI 
"rct.dev.bbntimes.com"
REDIRECT_REDIRECT_STATUS 
"200"
REDIRECT_REDIRECT_UNIQUE_ID 
"Z7mPY7iBoyj8JZ8-HGxyVgAAABQ"
REDIRECT_SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/covid-vaccines-and-the-nature-of-engineering"
REDIRECT_SCRIPT_URL 
"/science/covid-vaccines-and-the-nature-of-engineering"
REDIRECT_SSL_TLS_SNI 
"rct.dev.bbntimes.com"
REDIRECT_STATUS 
"200"
REDIRECT_UNIQUE_ID 
"Z7mPY7iBoyj8JZ8-HGxyVgAAABQ"
REDIRECT_URL 
"/public/science/covid-vaccines-and-the-nature-of-engineering"
REMOTE_ADDR 
"52.14.183.78"
REMOTE_PORT 
"60730"
REQUEST_METHOD 
"GET"
REQUEST_SCHEME 
"https"
REQUEST_TIME 
1740214115
REQUEST_TIME_FLOAT 
1740214115.1685
REQUEST_URI 
"/science/covid-vaccines-and-the-nature-of-engineering"
SCRIPT_FILENAME 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
SCRIPT_NAME 
"/public/index.php"
SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/covid-vaccines-and-the-nature-of-engineering"
SCRIPT_URL 
"/science/covid-vaccines-and-the-nature-of-engineering"
SERVER_ADDR 
"5.196.1.209"
SERVER_ADMIN 
"[no address given]"
SERVER_NAME 
"rct.dev.bbntimes.com"
SERVER_PORT 
"443"
SERVER_PROTOCOL 
"HTTP/1.1"
SERVER_SIGNATURE 
"<address>Apache Server at rct.dev.bbntimes.com Port 443</address>\n"
SERVER_SOFTWARE 
"Apache"
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App\Entity\Article {#1094
  -id: 7651
  -title: "COVID, Vaccines, and The Nature of Engineering"
  -slug: "covid-vaccines-and-the-nature-of-engineering"
  -introtext: "<p>Assuming one becomes available to you and/or your loved ones sometime soon, should you, or shouldn’t you, roll up your sleeve for a COVID vaccine?&nbsp;Please indulge me in a thought experiment on our shared way to my conclusion, and recommendation.</p>\r\n"
  -content: """
    \r\n
    <p>Imagine two teams of engineers- let’s call them teams A and B.&nbsp;One, Team A, is, arguably, the best that even the most vaccine reticent could possibly wish.&nbsp;Membership is reserved for the most monumentally experienced, wise, and venerable.&nbsp;The team is methodical, meticulous, and infinitely patient.&nbsp;As for their portfolio of accomplishments, let’s just say their products are completely dominant in the world, and their track record of success- although ascribed to various origins by different groups- is recognized, respected, and celebrated by all.</p>\r\n
    <p>The other team, B, is comprised of much younger, less experienced members.&nbsp;To be fair, however, these engineers are all highly and appropriately trained, and so far as we know or have cause to wonder, dedicated, smart, and caring.&nbsp;They are experienced, but much less so than the other team.&nbsp;They are, if anything, impatient- rather in contrast to their counterparts.&nbsp;While Team A occasionally surprises, their methods, efforts, and ends tend to follow a mostly reliable and often predictable pattern.&nbsp;Team B also relies on precedent, and builds on prior successes.&nbsp;However, Team B is more prone to shop for epiphanies, and engender surprises.&nbsp;Team B, we might say, operates with fewer rules; they are the “cowboys” of the engineering world.</p>\r\n
    <p>We can stop there, and pull back the curtains to reveal identities.&nbsp;Team B is made up of scientists- and in the specific instance of the COVID vaccines, the scientists working for&nbsp;<a href="https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/pfizer-biontech-covid-19-vaccine" target="_blank" rel="nofollow noopener">BioNTech and Pfizer</a>, those working for&nbsp;<a href="https://www.cnn.com/2020/12/17/health/moderna-vaccine-what-we-know/index.html" target="_blank" rel="nofollow noopener">Moderna</a>- and&nbsp;<a href="https://www.nature.com/articles/d41586-020-03563-z" target="_blank" rel="nofollow noopener">other such groups around the world</a>.</p>\r\n
    <p>Team A is…nature.&nbsp;We can anthropomorphize to facilitate the comparison, and say&nbsp;<em>Mother Nature</em>&nbsp;(she/her).&nbsp;We could detail the roster of members- evolutionary biology, natural selection, adaptation, mutation, etc.- but perhaps the “Science Team” versus the “Nature Team” will suffice.</p>\r\n
    <p>Perhaps you are thinking, almost reflexively, that you will go with Nature, thank you very much.&nbsp;You might be thinking that simply because, like me, you have an abiding reverence for the natural world, and see great prowess and wisdom in its working.&nbsp;In my case, and perhaps yours, that reverence is entirely secular.&nbsp;Or, perhaps your convictions are fueled by a more spiritual version of faith in Nature, perceiving marching orders from an even higher authority.&nbsp;Either way, you favor Team A, and are all the more vaccine reticent as a result.</p>\r\n
    <p>Trained and board-certified in both Internal Medicine, and Preventive Medicine/Public Health, and thus thoroughly schooled in relevant topics from&nbsp;<a href="https://www.elsevier.com/books/jekels-epidemiology-biostatistics-preventive-medicine-and-public-health/elmore/978-0-323-64201-9" target="_blank" rel="nofollow noopener">epidemiology</a>&nbsp;(the health of populations) to&nbsp;<a href="https://www.linkedin.com/pulse/covid19-seen-up-close-david-l-katz-md-mph-facpm-facp-faclm/" target="_blank" rel="noopener">patient care</a>,&nbsp;<a href="https://us.sagepub.com/en-us/nam/clinical-epidemiology-evidence-based-medicine/book8792" target="_blank" rel="nofollow noopener">evidence assessment</a>&nbsp;to iatrogenics (the inadvertent, but quite abundant harms of Medicine) - I have a long, unwavering, and unapologetic&nbsp;<a href="https://www.linkedin.com/pulse/20130722112534-23027997-the-anti-anti-vaccine-argument/" target="_blank" rel="noopener">history of defending the profound, clearly established net value of vaccines</a>&nbsp;to public health.&nbsp;That said, I do understand and empathize with a naturalistic longing.&nbsp;For years, I directed an&nbsp;<a href="https://www.planetree.nl/mijnplanetree/wp-content/uploads/2016/06/Internationaal-katz-article-integrative-medicine-2003.pdf" target="_blank" rel="nofollow noopener">Integrative Medicine Center</a>, working alongside colleagues trained in natural medicine (and, by the way, committed to&nbsp;<a href="https://pubmed.ncbi.nlm.nih.gov/26477898/" target="_blank" rel="nofollow noopener">scientific evidence</a>)- and we cared for those who favored natural treatment by disposition, or who came to seek it after conventional medicine’s greatest hits failed to fix what ailed them.&nbsp;That is, alas, far from uncommon.&nbsp;And, Nature’s allure may be enhanced for us all as our technologized, modern existence puts her at ever greater remove.&nbsp;The grass, as they say, is always greener on the other side of the 5G tower.</p>\r\n
    <p>So, I appreciate your inclinations toward Team A.&nbsp;But before you cast your lot there, which in our current plight might mean favoring your chances without a vaccine- let us push our thought experiment in one more direction.</p>\r\n
    <p>Imagine, if you would, an injured impala.&nbsp;The injury in question is to a leg, is not too serious, would heal fully in time- but for now, is seriously affecting speed.</p>\r\n
    <p>The remedy of science for this scenario would likely be an animal rehab center.&nbsp;The animal, if detected and a target of our ministrations, would be tranquilized, transported, and treated, then given time to strengthen and mend.&nbsp;After that, it would be returned to the wild where it might well thrive for years, and produce offspring.</p>\r\n
    <p>Nature, too, has a remedy for an impala with an injured leg: a hungry cheetah.&nbsp;</p>\r\n
    <p>Nature’s method is decisively brutal for the impala, but swift and certainly effective.&nbsp;The injured leg ceases to be anyone’s problem, and proves to be the cheetah family’s boon.&nbsp;If I may indulge in a quip: Cheetahs do indeed prosper when fate is unkind to impala.</p>\r\n
    <p>You see the point?&nbsp;Sure, nature is a fabulous engineer.&nbsp;So, sure, you might prefer her products to our own.&nbsp;But as often as not, she is working for the other side.</p>\r\n
    <p>Nature- natural selection- designed the extraordinary defenses of human physiology. But she also designed rattlesnake venom that undoes them.&nbsp;She designed the remarkable array of lymphocytes that patrol our inner byways of lymph and blood- but she also designed HIV that has been deluding, defying, and decimating those lymphocytes for the past 40 years.&nbsp;The remarkable intricacies of our immune system are all to her credit.&nbsp;So is SARS-CoV-2.</p>\r\n
    <p>If you favor Nature over the machinations of our own science, I have no argument with you.&nbsp;In time we may mature in both knowledge and wisdom to compete more favorably, but we are not there yet.&nbsp;Overall, to date, our science has done more harm than good to the elegant balance of the natural world we were bequeathed.&nbsp;Nature is the better engineer.</p>\r\n
    <p>Our own, still maturing efforts are, however, occasionally quite brilliant- and there is certainly cause to trust, and employ their products at times.&nbsp;Because Nature’s greater aptitude comes with a casual indifference to the fate of individuals.&nbsp;Her engineering is not directed to the contestants, but to the contest; not to a winner, but to equilibrium.&nbsp;One imagines the venerable engineers of natural selection, observing the wins and losses of impala and cheetah alike, saying: “<em>nothing personal</em>.”&nbsp;</p>\r\n
    <p>If it is your faith in nature that calls up your reticence about science in general, or the COVID vaccines specifically, you are right about her prowess, but wrong about her patronage.&nbsp;</p>\r\n
    <p>Mother Nature harbors no bias for predator or prey.&nbsp;If she did, her favorite would multiply at the expense of its counterpart, and that would be the doom of both.&nbsp;If she can be spoken of in terms of favorites at all, Mother Nature favors balance- the elaborate equilibria detailed in all their mathematical glory by Richard Dawkins in&nbsp;<a href="https://www.amazon.com/Selfish-Gene-Popular-Science/dp/0192860925" target="_blank" rel="nofollow noopener"><em>The Selfish Gene</em></a>.&nbsp;She reliably prefers neither predator nor prey, but rather the close-run contest between them- as only that ensures the survival of both, in the balance of her dominion.</p>\r\n
    <p>We Homo sapiens are long accustomed to being the predator.&nbsp;In the pandemic, however, we are prey.&nbsp;The predator in this instance, too small to see, stalks our cells.&nbsp;Mother Nature incubated those cells in her “lab.”&nbsp;She incubated SARS-CoV-2 there as well.</p>\r\n
    <p>So now, the matter of your vaccine- or for that matter, mine.&nbsp;Yes, I will certainly be vaccinated against COVID when that opportunity reaches me (I am not seeing patients now, so I am far from first in line).&nbsp;I will film the experience and share it so you needn’t take my word for it.</p>\r\n
    <p>I will be vaccinated not because I think the vaccine carries zero risk-&nbsp;<a href="https://www.nytimes.com/2020/12/16/health/covid-pfizer-vaccine-allergic-reaction.html" target="_blank" rel="nofollow noopener">I know the opposite to be true</a>.&nbsp;And, sure, I would really like to have data about the long-term effects (i.e., years) of the vaccine first.&nbsp;But we don’t have years-long data about the virus, either, and for all we know there could be late consequences of infection.&nbsp;Let’s be clear, the only risk-free pandemic option is not to be in a pandemic.&nbsp;Once in one, our options all involve risk.&nbsp;The lesser risk is the best we can now do.</p>\r\n
    <p>The adjudication of that risk is neither stable over time, nor a one-size-fits-all proposition.&nbsp;As for time, the virus is currently so widespread in the U.S. as I write this, as to situate COVID, temporarily,&nbsp;<a href="https://jamanetwork.com/journals/jama/fullarticle/2774465" target="_blank" rel="nofollow noopener">at or near the top causes of death</a>&nbsp;for those over age 35.&nbsp;The greater the risks of unprotected exposure, the greater the relative merits of vaccination.</p>\r\n
    <p>Those risks do vary, however, by age and health status- the very point I have been hammering at&nbsp;<a href="https://www.linkedin.com/pulse/am-i-going-get-coronavirus-die-l-katz-md-mph-facpm-facp-faclm/" target="_blank" rel="noopener">from the start of all this</a>.&nbsp;Vaccine distribution policies are predicated on stratified risk (it’s&nbsp;<a href="https://www.linkedin.com/pulse/covid-con-tempo-what-can-america-do-now-david/" target="_blank" rel="noopener">about time something to do with our pandemic response is</a>!), and your decision making might quite reasonably be, as well.&nbsp;If young, healthy, and not prone to interact with, and thus potentially transmit SARS-CoV-2 to, anyone without those same advantages- you might safely defer vaccination.&nbsp;But few are those islands among us, and the scales of relative risk tip the other way for most of us.&nbsp;After all, the best available expertise has been directed at minimizing any potential harms of vaccination; the same cannot be said of SARS-CoV-2.</p>\r\n
    <p>To reiterate, I have&nbsp;<a href="https://www.huffpost.com/entry/flu-shot_b_2257520" target="_blank" rel="nofollow noopener">always championed the general merits of vaccination</a>.&nbsp;I was dubious that COVID vaccines would arrive in time to do us much good, and accordingly&nbsp;<a href="https://www.truehealthinitiative.org/covid/" target="_blank" rel="nofollow noopener">emphasized other aspects of pandemic management</a>&nbsp;I still believe and maintain could have much mitigated&nbsp;<a href="https://www.linkedin.com/pulse/epic-pandemic-mismanagement-how-why-david/" target="_blank" rel="noopener">the collective toll we have suffered</a>.&nbsp;But here we are- those opportunities mostly behind us, vaccination- directly ahead.&nbsp;Our current choices between here and the pandemic terminus distill substantially to taking chances with the virus, or choosing immunization against it.</p>\r\n
    <p>Taking Nature’s chances may appeal, just because they issue from nature.&nbsp;But let’s concede that Mother Nature is not reliably on our side; it’s our job to be on hers.&nbsp;Uniformly favoring the engineering of Nature fails to consider the nature and objectives of her engineering. The pandemic harbors many lessons on that very matter - climate change, many more.&nbsp;&nbsp;We ignore those, in any context, at our peril.</p>\r\n
    <p>We rely on Nature’s engineering to save us, or even necessarily serve us, at our peril, as well.&nbsp;Yes, we are beneficiaries of Team A’s extraordinary engineering prowess.&nbsp;But in that, we are not alone.&nbsp;Team A, after all, engineered the virus, too.</p>
    """
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