GET https://rct.dev.bbntimes.com/science/digital-health-has-converged-with-biopharma

ArticleController :: show

Request

GET Parameters

None

POST Parameters

None

Uploaded Files

None

Request Attributes

Key Value
_controller
"App\Controller\ArticleController::show"
_firewall_context
"security.firewall.map.context.main"
_links
Symfony\Component\WebLink\GenericLinkProvider {#3638
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    3755 => Symfony\Component\WebLink\Link {#3755
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    3751 => Symfony\Component\WebLink\Link {#3751
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    3750 => Symfony\Component\WebLink\Link {#3750
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      -rel: [
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      -attributes: [
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    3749 => Symfony\Component\WebLink\Link {#3749
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      ]
    }
    3748 => Symfony\Component\WebLink\Link {#3748
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    3747 => Symfony\Component\WebLink\Link {#3747
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    3746 => Symfony\Component\WebLink\Link {#3746
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      -rel: [
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      -attributes: [
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_route
"article_show"
_route_params
[
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_security_firewall_run
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_stopwatch_token
"426489"
category
"science"
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"digital-health-has-converged-with-biopharma"

Request Headers

Header Value
accept
"*/*"
accept-encoding
"gzip, br, zstd, deflate"
connection
"close"
cookie
"user_agent=Mozilla%2F5.0%20AppleWebKit%2F537.36%20%28KHTML%2C%20like%20Gecko%3B%20compatible%3B%20ClaudeBot%2F1.0%3B%20%2Bclaudebot%40anthropic.com%29; handl_ip=3.144.34.97; handl_url_base=https%3A%2F%2Fpulse360.com%2Fblog%2Fcustomer-advisory-board-best-practices; HandLtestDomainNameServer=HandLtestDomainValueServer; handl_landing_page=https%3A%2F%2Fpulse360.com%2Fblog%2Fcustomer-advisory-board-best-practices; handl_url=https%3A%2F%2Fpulse360.com%2Fblog%2Fcustomer-advisory-board-best-practices; PHPSESSID=ibruedtrvmgfmobsn52as6ko19"
host
"rct.dev.bbntimes.com"
user-agent
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
x-php-ob-level
"1"

Request Content

Request content not available (it was retrieved as a resource).

Response

Response Headers

Header Value
cache-control
"no-cache, private"
content-type
"text/html; charset=UTF-8"
date
"Sat, 22 Feb 2025 08:47:56 GMT"
link
"</build/runtime.js>; rel="preload"; as="script",</build/644.js>; rel="preload"; as="script",</build/502.js>; rel="preload"; as="script",</build/app.js>; rel="preload"; as="script",</build/view-more.js>; rel="preload"; as="script",</build/term-condition.js>; rel="preload"; as="script",</build/contact.js>; rel="preload"; as="script",</build/scroll-infinite-article.js>; rel="preload"; as="script",</build/app.css>; rel="preload"; as="style",</build/cookie-style.css>; rel="preload"; as="style",</build/term-condition-css.css>; rel="preload"; as="style",</build/contact-css.css>; rel="preload"; as="style",</build/comment-css.css>; rel="preload"; as="style""
x-debug-token
"6681ee"

Cookies

Request Cookies

Key Value
HandLtestDomainNameServer
"HandLtestDomainValueServer"
PHPSESSID
"ibruedtrvmgfmobsn52as6ko19"
handl_ip
"3.144.34.97"
handl_landing_page
"https://pulse360.com/blog/customer-advisory-board-best-practices"
handl_url
"https://pulse360.com/blog/customer-advisory-board-best-practices"
handl_url_base
"https://pulse360.com/blog/customer-advisory-board-best-practices"
user_agent
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"

Response Cookies

No response cookies

Session 6

Session Metadata

Key Value
Created
"Sat, 22 Feb 25 08:47:32 +0000"
Last used
"Sat, 22 Feb 25 08:47:53 +0000"
Lifetime
0

Session Attributes

Attribute Value
_csrf/https-comment
"GV_nHPN3bQ_mr99NgBgYv6nle_64Bcj-SIX44bOEQA0"
_csrf/https-cookie_accept
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Session Usage

6 Usages
Stateless check enabled
Usage
Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:76
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:79
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    "line" => 95
    "function" => "finishView"
    "class" => "Symfony\Component\Form\ResolvedFormType"
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    "line" => 908
    "function" => "finishView"
    "class" => "Symfony\Component\Form\Extension\DataCollector\Proxy\ResolvedTypeDataCollectorProxy"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/src/Controller/ArticleController.php"
    "line" => 220
    "function" => "createView"
    "class" => "Symfony\Component\Form\Form"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 181
    "function" => "show"
    "class" => "App\Controller\ArticleController"
    "type" => "->"
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    "function" => "handleRaw"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
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    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
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  [
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    "line" => 35
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\Kernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    "line" => 29
    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
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]
Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage:41
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-core/Authentication/Token/Storage/UsageTrackingTokenStorage.php"
    "line" => 41
    "function" => "getMetadataBag"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
    "type" => "->"
  ]
  [
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    "line" => 103
    "function" => "getToken"
    "class" => "Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage"
    "type" => "->"
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    "line" => 1635
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    "function" => "twig_get_attribute"
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    "function" => "displayWithErrorHandling"
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    "function" => "display"
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    "function" => "render"
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    "function" => "render"
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  [
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    "function" => "handle"
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  [
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    "function" => "handle"
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    "function" => "displayWithErrorHandling"
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    "line" => 379
    "function" => "display"
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  [
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    "function" => "render"
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    "function" => "render"
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  [
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    "line" => 453
    "function" => "doRenderView"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
    "type" => "->"
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    "line" => 253
    "function" => "doRender"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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  ]
  [
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    "function" => "render"
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    "function" => "show"
    "class" => "App\Controller\ArticleController"
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    "function" => "handleRaw"
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    "type" => "->"
  ]
  [
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    "line" => 197
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/runtime/Runner/Symfony/HttpKernelRunner.php"
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    "function" => "handle"
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    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
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  [
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    "line" => 5
    "args" => [
      "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    ]
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]
Symfony\Component\Security\Http\Firewall\ContextListener:171
[
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    "line" => 171
    "function" => "remove"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/Debug/WrappedListener.php"
    "line" => 116
    "function" => "onKernelResponse"
    "class" => "Symfony\Component\Security\Http\Firewall\ContextListener"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/EventDispatcher.php"
    "line" => 220
    "function" => "__invoke"
    "class" => "Symfony\Component\EventDispatcher\Debug\WrappedListener"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/EventDispatcher.php"
    "line" => 56
    "function" => "callListeners"
    "class" => "Symfony\Component\EventDispatcher\EventDispatcher"
    "type" => "->"
  ]
  [
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    "function" => "dispatch"
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    "function" => "dispatch"
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  [
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    "line" => 202
    "function" => "filterResponse"
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    "function" => "handle"
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    "function" => "run"
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    "function" => "require_once"
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]

Flashes

Flashes

No flash messages were created.

Server Parameters

Server Parameters

Defined in .env

Key Value
APP_ENV
"dev"
APP_SECRET
"0a988e63f011514eaabfc650b599af4d"
CORS_ALLOW_ORIGIN
"*"
DATABASE_URL
"mysql://bbndb_rctuser:33F5W25z40or0f7@localhost:3306/rct_bbntimes"
GOOGLE_RECAPTCHA_SECRET_KEY
"6LdV5fgpAAAAANxzTG8ZMfIjil1wu-1vrQvnUt-x"
GOOGLE_RECAPTCHA_SITE_KEY
"6LdV5fgpAAAAAENKcn73MJAhQrbtQeqgyC4wDLMP"
MAILER_DSN
"smtp://no-reply%40rct.dev.bbntimes.com:Bl6%26gLD48%26Of919@rct.dev.bbntimes.com:465"
MARIADB_PASSWORD
"i!87pK&!85ezc8"

Defined as regular env variables

Key Value
APP_DEBUG
"1"
BASE
"/public"
CONTEXT_DOCUMENT_ROOT
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
CONTEXT_PREFIX
""
DOCUMENT_ROOT
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
FCGI_ROLE
"RESPONDER"
GATEWAY_INTERFACE
"CGI/1.1"
HTTPS
"on"
HTTP_ACCEPT
"*/*"
HTTP_ACCEPT_ENCODING
"gzip, br, zstd, deflate"
HTTP_CONNECTION
"close"
HTTP_COOKIE
"user_agent=Mozilla%2F5.0%20AppleWebKit%2F537.36%20%28KHTML%2C%20like%20Gecko%3B%20compatible%3B%20ClaudeBot%2F1.0%3B%20%2Bclaudebot%40anthropic.com%29; handl_ip=3.144.34.97; handl_url_base=https%3A%2F%2Fpulse360.com%2Fblog%2Fcustomer-advisory-board-best-practices; HandLtestDomainNameServer=HandLtestDomainValueServer; handl_landing_page=https%3A%2F%2Fpulse360.com%2Fblog%2Fcustomer-advisory-board-best-practices; handl_url=https%3A%2F%2Fpulse360.com%2Fblog%2Fcustomer-advisory-board-best-practices; PHPSESSID=ibruedtrvmgfmobsn52as6ko19"
HTTP_HOST
"rct.dev.bbntimes.com"
HTTP_USER_AGENT
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY
"0"
PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY
"0"
PATH
"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/sbin:/bin:/snap/bin"
PHP_SELF
"/public/index.php"
PP_CUSTOM_PHP_CGI_INDEX
"plesk-php81-fastcgi"
PP_CUSTOM_PHP_INI
"/var/www/vhosts/system/rct.dev.bbntimes.com/etc/php.ini"
QUERY_STRING
""
REDIRECT_BASE
"/public"
REDIRECT_HTTPS
"on"
REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY
"0"
REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY
"0"
REDIRECT_REDIRECT_HTTPS
"on"
REDIRECT_REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY
"0"
REDIRECT_REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY
"0"
REDIRECT_REDIRECT_SCRIPT_URI
"https://rct.dev.bbntimes.com/science/digital-health-has-converged-with-biopharma"
REDIRECT_REDIRECT_SCRIPT_URL
"/science/digital-health-has-converged-with-biopharma"
REDIRECT_REDIRECT_SSL_TLS_SNI
"rct.dev.bbntimes.com"
REDIRECT_REDIRECT_STATUS
"200"
REDIRECT_REDIRECT_UNIQUE_ID
"Z7mPO7iBoyj8JZ8-HGxyKwAAAAk"
REDIRECT_SCRIPT_URI
"https://rct.dev.bbntimes.com/science/digital-health-has-converged-with-biopharma"
REDIRECT_SCRIPT_URL
"/science/digital-health-has-converged-with-biopharma"
REDIRECT_SSL_TLS_SNI
"rct.dev.bbntimes.com"
REDIRECT_STATUS
"200"
REDIRECT_UNIQUE_ID
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REDIRECT_URL
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Sub Requests 6

CookieController :: renderAnalysis (token = 071a18)

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AppController :: renderHeader (token = d62a14)

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ArticleController :: trendingArticle (token = d1e652)

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ArticleController :: relatedArticles (token = 8d7e24)

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App\Entity\Article {#1094
  -id: 7181
  -title: "Digital Health Has Converged with Biopharma"
  -slug: "digital-health-has-converged-with-biopharma"
  -introtext: """
    <div id="ember72" class="ember-view">\r\n
    <div class="reader-article-content" dir="ltr">\r\n
    <p><span style="color: #000000;">The convergence has happened because digital health technologies are making it easier for biopharmaceutical companies to discover, develop and launch new drugs faster and cheaper and improve the patient and doctor experience, in what is being labeled "after the pill".</span></p>\r\n
    """
  -content: """
    \r\n
    <p class="p1"><span class="s1">U.S. regulators have approved the first digital pill with an embedded sensor to track if patients are taking their medication properly, marking a significant step forward in the convergence of healthcare and technology.&nbsp;</span><span class="s2"><span style="color: #000000;">Some, however,&nbsp;are voicing&nbsp;</span><span class="s1">concerns</span></span><span class="s1"> </span><span class="s2" style="color: #000000;">that there is no evidence that digital pills, prescription medications with ingestible wireless sensors, are beneficial to patients and, in fact, the technology poses a danger to the provider-patient relationship.</span></p>\r\n
    <p class="p1"><span class="s2"><span style="color: #000000;">Increasingly, we are seeing the results of the intersection of digital health, biopharma, and MedTech.&nbsp;Here is an update on digital health pharma news. Here is an</span>&nbsp;<span class="s1">update&nbsp;</span><span style="color: #000000;">on digital health pharma news.</span></span></p>\r\n
    <h2><span style="color: #10228b;">The Next Stage of Pharma and Digital Health Collaborations</span></h2>\r\n
    <p><span style="color: #000000;">Recent medical developments have gone towards personalized healthcare, meaning that patients get individualized treatments for their specific needs and also manage their disease.</span></p>\r\n
    <p><span style="color: #000000;">Buzzwords that come to my mind in this context include big data, artificial intelligence, closed-loop systems (not only for diabetes), and precision medicine.</span></p>\r\n
    <p>Here are the results of a recent survey about the use of digital health in biopharma.</p>\r\n
    <h2><span style="color: #10228b;">Applications of Digital Health in Biopharma</span></h2>\r\n
    <p><span style="color: #000000;">There are many applications:</span></p>\r\n
    <ul>\r\n
    <li><span style="color: #000000;">Drug discovery and development using community-based innovation networks</span></li>\r\n
    <li><span style="color: #000000;">Better clinical trial recruitment, retention and execution</span></li>\r\n
    <li><span style="color: #000000;">Physician engagement</span></li>\r\n
    <li><span style="color: #000000;">Patient engagement, compliance and adherence</span></li>\r\n
    <li><span style="color: #000000;">Information and education.&nbsp;</span>Here's how digital health technologies are helping patients with diabetes and hypertension.</li>\r\n
    <li><span style="color: #000000;">Remote sensing, data, and analytics. For example, Pittsburgh-based</span>&nbsp;UPMC Enterprises&nbsp;<span style="color: #000000;">has&nbsp;made&nbsp;an equity investment in RxAnte, a predictive analytics and clinical intervention solution provider focused on inappropriate medication use.&nbsp;RxAnte uses predictive analytics to improve prescribing practices and appropriate use of prescription medications.</span></li>\r\n
    <li><span style="color: #000000;">Post market surveillance and pharmacovigilence</span></li>\r\n
    <li><span style="color: #000000;">Sales and marketing</span></li>\r\n
    <li><span style="color: #000000;">Personalized and precision medicine</span></li>\r\n
    <li><span style="color: #000000;">Price and effectiveness transparency</span></li>\r\n
    <li><span style="color: #000000;">Drug delivery</span></li>\r\n
    <li><span style="color: #000000;">Smart Pills</span></li>\r\n
    </ul>\r\n
    <p><span style="color: #000000;">In addition, artificial intelligence, machine learning and blockchain technologies have the potential to improve the research quotient of biopharma drug discovery and development:</span></p>\r\n
    <h2><span style="color: #10228b;">3 Predictions for AI in Pharma R&amp;D in the Year Ahead</span></h2>\r\n
    <ul>\r\n
    <li><span style="color: #000000;"><strong>Prediction 1:</strong>&nbsp;Drug discovery is being redefined by advances in technology. AI and machine learning software is expanding the universe of screenable compounds and will deliver higher hit rates as compounds move through the pharma value chain. The race is on for data.</span></li>\r\n
    <li><span style="color: #000000;"><strong>Prediction 2:</strong>&nbsp;Within the next 10 years, a blockbuster-potential drug will emerge from a process that started with a computer, then to the bench, then to the clinic. We will see within the next few years promising compounds enter the FDA pipeline.</span></li>\r\n
    <li><span style="color: #000000;"><strong>Prediction 3:</strong>&nbsp;Pharma companies will step up M&amp;A, investment and joint venture activity this year and in 2019 as they look to the world of software AI startups for new drug discovery capabilities. The tailwinds are there for tremendous value creation.</span></li>\r\n
    </ul>\r\n
    <p><span style="color: #000000;">Going beyond the pill will also require&nbsp;new business models&nbsp;and faces the challenges of precision medicine.</span></p>\r\n
    <p><span style="color: #000000;">Using digital tools to innovate has moved biopharmaceutical companies to create a new position:&nbsp;chief digital officer&nbsp;and they are developing best practices.</span></p>\r\n
    <p><span style="color: #000000;">All of these opportunities will challenge STEM graduate and medical school educators and leaders to create new learning objectives that provide the new and necessary competencies for graduates to compete in these evolving industries, particularly in the areas of data science, analytics, mining unstructured data, and intelligence. Some universities and health systems,&nbsp;like the&nbsp;University of Colorado,&nbsp;are doing just that. They are also&nbsp;partnering with</span>&nbsp;Startup Health&nbsp;<span style="color: #000000;">to help entrepreneurs, end users and investors create products and services that fill this market need.</span></p>\r\n
    <p>Here is the McKinsey perspective on what Medical Affairs will face in 2025 and the opportunities it presents for physician entrepreneurs.&nbsp;<span style="color: #000000;">The 2025 medical science liaison will have to meet the needs of patients and doctors.&nbsp;How many sickcare professionals do you know who are comfortable with digital marketing, big data and analytics, comparative effective research, design to value, the business of biopharma and communicating with increasingly diverse stakeholders?</span></p>\r\n
    <p><span style="color: #000000;">Digital health technologies are changing not only the face of clinical practice entrepreneurship but MedTech and biopharma as well. Given the pace of change, we are likely to see Digital Biopharma 2.0 and&nbsp;Digital Medtech 2.0&nbsp;in the blink of an app. In fact,&nbsp;we might already have&nbsp;missed&nbsp;it.</span><br /><br /></p>\r\n
    <p><span style="color: #000000;">Arlen Meyers, MD, MBA is the President and CEO of the</span>&nbsp;Society of Physician Entrepreneurs.</p>\r\n
    </div>\r\n
    </div>
    """
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    date: 2021-05-19 13:39:33.0 UTC (+00:00)
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AppController :: renderFooter (token = 50fae1)

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CookieController :: renderCookie (token = cc18dd)

Key Value
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"App\Controller\CookieController::renderCookie"
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"en"
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