GET https://rct.dev.bbntimes.com/science/digital-health-therapeutics-issues-and-opportunities

Response
200 OK
IP
3.145.66.134
Profiled on
Token
674299

ArticleController :: show

Request

GET Parameters

None

POST Parameters

None

Uploaded Files

None

Request Attributes

Key Value
_controller 
"App\Controller\ArticleController::show"
_firewall_context 
"security.firewall.map.context.main"
_links 
Symfony\Component\WebLink\GenericLinkProvider {#3638
  -links: [
    3759 => Symfony\Component\WebLink\Link {#3759
      -href: "/build/runtime.js"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "script"
      ]
    }
    3757 => Symfony\Component\WebLink\Link {#3757
      -href: "/build/644.js"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "script"
      ]
    }
    3756 => Symfony\Component\WebLink\Link {#3756
      -href: "/build/502.js"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "script"
      ]
    }
    3755 => Symfony\Component\WebLink\Link {#3755
      -href: "/build/app.js"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "script"
      ]
    }
    3754 => Symfony\Component\WebLink\Link {#3754
      -href: "/build/view-more.js"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "script"
      ]
    }
    3753 => Symfony\Component\WebLink\Link {#3753
      -href: "/build/term-condition.js"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "script"
      ]
    }
    3752 => Symfony\Component\WebLink\Link {#3752
      -href: "/build/contact.js"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "script"
      ]
    }
    3751 => Symfony\Component\WebLink\Link {#3751
      -href: "/build/scroll-infinite-article.js"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "script"
      ]
    }
    3750 => Symfony\Component\WebLink\Link {#3750
      -href: "/build/app.css"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "style"
      ]
    }
    3749 => Symfony\Component\WebLink\Link {#3749
      -href: "/build/cookie-style.css"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "style"
      ]
    }
    3748 => Symfony\Component\WebLink\Link {#3748
      -href: "/build/term-condition-css.css"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "style"
      ]
    }
    3747 => Symfony\Component\WebLink\Link {#3747
      -href: "/build/contact-css.css"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "style"
      ]
    }
    3746 => Symfony\Component\WebLink\Link {#3746
      -href: "/build/comment-css.css"
      -rel: [
        "preload" => "preload"
      ]
      -attributes: [
        "as" => "style"
      ]
    }
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}
_route 
"article_show"
_route_params 
[
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  "slug" => "digital-health-therapeutics-issues-and-opportunities"
]
_security_firewall_run 
"_security_main"
_stopwatch_token 
"02e73b"
category 
"science"
slug 
"digital-health-therapeutics-issues-and-opportunities"

Request Headers

Header Value
accept 
"*/*"
accept-encoding 
"gzip, br, zstd, deflate"
connection 
"close"
cookie 
"care_did=e77f029a-c163-41cb-b0cc-65ac612eac05; PHPSESSID=rjvkgm1pd8obqmqlenum1j5ecq"
host 
"rct.dev.bbntimes.com"
user-agent 
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
x-php-ob-level 
"1"

Request Content

Request content not available (it was retrieved as a resource).

Response

Response Headers

Header Value
cache-control 
"no-cache, private"
content-type 
"text/html; charset=UTF-8"
date 
"Sat, 22 Feb 2025 13:38:26 GMT"
link 
"</build/runtime.js>; rel="preload"; as="script",</build/644.js>; rel="preload"; as="script",</build/502.js>; rel="preload"; as="script",</build/app.js>; rel="preload"; as="script",</build/view-more.js>; rel="preload"; as="script",</build/term-condition.js>; rel="preload"; as="script",</build/contact.js>; rel="preload"; as="script",</build/scroll-infinite-article.js>; rel="preload"; as="script",</build/app.css>; rel="preload"; as="style",</build/cookie-style.css>; rel="preload"; as="style",</build/term-condition-css.css>; rel="preload"; as="style",</build/contact-css.css>; rel="preload"; as="style",</build/comment-css.css>; rel="preload"; as="style""
x-debug-token 
"674299"

Cookies

Request Cookies

Key Value
PHPSESSID 
"rjvkgm1pd8obqmqlenum1j5ecq"
care_did 
"e77f029a-c163-41cb-b0cc-65ac612eac05"

Response Cookies

No response cookies

Session 6

Session Metadata

Key Value
Created 
"Sat, 22 Feb 25 13:38:13 +0000"
Last used 
"Sat, 22 Feb 25 13:38:25 +0000"
Lifetime 
0

Session Attributes

Attribute Value
_csrf/https-comment 
"GXjxwd-fluBHGPCe2HBtx2Rhmyraff_UBBAdvcv4EHU"
_csrf/https-cookie_accept 
"y4iTr0XLM9wiXFLnRkJhzgIR3goLlcmJgwxIz5APEVc"

Session Usage

6 Usages
Stateless check enabled
Usage
Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:76
Show trace 
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:79
Show trace 
[
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:52
Show trace 
[
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:56
Show trace 
[
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    "line" => 181
    "function" => "show"
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    "type" => "->"
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    "function" => "handleRaw"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
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  [
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    "line" => 197
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
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  [
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    "line" => 35
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\Kernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    "line" => 29
    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
    "line" => 5
    "args" => [
      "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    ]
    "function" => "require_once"
  ]
]
Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage:41
Show trace 
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-core/Authentication/Token/Storage/UsageTrackingTokenStorage.php"
    "line" => 41
    "function" => "getMetadataBag"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/twig-bridge/AppVariable.php"
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    "function" => "getToken"
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    "function" => "twig_get_attribute"
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    "function" => "display"
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    "class" => "Twig\Template"
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    "function" => "render"
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    "line" => 453
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    "function" => "doRender"
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  [
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    "function" => "render"
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    "function" => "show"
    "class" => "App\Controller\ArticleController"
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    "function" => "handleRaw"
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    "type" => "->"
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  [
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    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
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  [
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    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\Kernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    "line" => 29
    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
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  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
    "line" => 5
    "args" => [
      "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    ]
    "function" => "require_once"
  ]
]
Symfony\Component\Security\Http\Firewall\ContextListener:171
Show trace 
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-http/Firewall/ContextListener.php"
    "line" => 171
    "function" => "remove"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/Debug/WrappedListener.php"
    "line" => 116
    "function" => "onKernelResponse"
    "class" => "Symfony\Component\Security\Http\Firewall\ContextListener"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/EventDispatcher.php"
    "line" => 220
    "function" => "__invoke"
    "class" => "Symfony\Component\EventDispatcher\Debug\WrappedListener"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/EventDispatcher.php"
    "line" => 56
    "function" => "callListeners"
    "class" => "Symfony\Component\EventDispatcher\EventDispatcher"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/Debug/TraceableEventDispatcher.php"
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    "function" => "dispatch"
    "class" => "Symfony\Component\EventDispatcher\EventDispatcher"
    "type" => "->"
  ]
  [
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    "function" => "dispatch"
    "class" => "Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
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    "function" => "filterResponse"
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    "function" => "handleRaw"
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    "function" => "handle"
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    "function" => "run"
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]

Flashes

Flashes

No flash messages were created.

Server Parameters

Server Parameters

Defined in .env

Key Value
APP_ENV 
"dev"
APP_SECRET 
"0a988e63f011514eaabfc650b599af4d"
CORS_ALLOW_ORIGIN 
"*"
DATABASE_URL 
"mysql://bbndb_rctuser:33F5W25z40or0f7@localhost:3306/rct_bbntimes"
GOOGLE_RECAPTCHA_SECRET_KEY 
"6LdV5fgpAAAAANxzTG8ZMfIjil1wu-1vrQvnUt-x"
GOOGLE_RECAPTCHA_SITE_KEY 
"6LdV5fgpAAAAAENKcn73MJAhQrbtQeqgyC4wDLMP"
MAILER_DSN 
"smtp://no-reply%40rct.dev.bbntimes.com:Bl6%26gLD48%26Of919@rct.dev.bbntimes.com:465"
MARIADB_PASSWORD 
"i!87pK&!85ezc8"

Defined as regular env variables

Key Value
APP_DEBUG 
"1"
BASE 
"/public"
CONTEXT_DOCUMENT_ROOT 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
CONTEXT_PREFIX 
""
DOCUMENT_ROOT 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
FCGI_ROLE 
"RESPONDER"
GATEWAY_INTERFACE 
"CGI/1.1"
HTTPS 
"on"
HTTP_ACCEPT 
"*/*"
HTTP_ACCEPT_ENCODING 
"gzip, br, zstd, deflate"
HTTP_CONNECTION 
"close"
HTTP_COOKIE 
"care_did=e77f029a-c163-41cb-b0cc-65ac612eac05; PHPSESSID=rjvkgm1pd8obqmqlenum1j5ecq"
HTTP_HOST 
"rct.dev.bbntimes.com"
HTTP_USER_AGENT 
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
PATH 
"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/sbin:/bin:/snap/bin"
PHP_SELF 
"/public/index.php"
PP_CUSTOM_PHP_CGI_INDEX 
"plesk-php81-fastcgi"
PP_CUSTOM_PHP_INI 
"/var/www/vhosts/system/rct.dev.bbntimes.com/etc/php.ini"
QUERY_STRING 
""
REDIRECT_BASE 
"/public"
REDIRECT_HTTPS 
"on"
REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_HTTPS 
"on"
REDIRECT_REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/digital-health-therapeutics-issues-and-opportunities"
REDIRECT_REDIRECT_SCRIPT_URL 
"/science/digital-health-therapeutics-issues-and-opportunities"
REDIRECT_REDIRECT_SSL_TLS_SNI 
"rct.dev.bbntimes.com"
REDIRECT_REDIRECT_STATUS 
"200"
REDIRECT_REDIRECT_UNIQUE_ID 
"Z7nTUbiBoyj8JZ8-HGyF5gAAAAw"
REDIRECT_SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/digital-health-therapeutics-issues-and-opportunities"
REDIRECT_SCRIPT_URL 
"/science/digital-health-therapeutics-issues-and-opportunities"
REDIRECT_SSL_TLS_SNI 
"rct.dev.bbntimes.com"
REDIRECT_STATUS 
"200"
REDIRECT_UNIQUE_ID 
"Z7nTUbiBoyj8JZ8-HGyF5gAAAAw"
REDIRECT_URL 
"/public/science/digital-health-therapeutics-issues-and-opportunities"
REMOTE_ADDR 
"3.145.66.134"
REMOTE_PORT 
"27743"
REQUEST_METHOD 
"GET"
REQUEST_SCHEME 
"https"
REQUEST_TIME 
1740231506
REQUEST_TIME_FLOAT 
1740231506.0047
REQUEST_URI 
"/science/digital-health-therapeutics-issues-and-opportunities"
SCRIPT_FILENAME 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
SCRIPT_NAME 
"/public/index.php"
SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/digital-health-therapeutics-issues-and-opportunities"
SCRIPT_URL 
"/science/digital-health-therapeutics-issues-and-opportunities"
SERVER_ADDR 
"5.196.1.209"
SERVER_ADMIN 
"[no address given]"
SERVER_NAME 
"rct.dev.bbntimes.com"
SERVER_PORT 
"443"
SERVER_PROTOCOL 
"HTTP/1.1"
SERVER_SIGNATURE 
"<address>Apache Server at rct.dev.bbntimes.com Port 443</address>\n"
SERVER_SOFTWARE 
"Apache"
SSL_TLS_SNI 
"rct.dev.bbntimes.com"
SYMFONY_DOTENV_VARS 
"APP_ENV,APP_SECRET,DATABASE_URL,MARIADB_PASSWORD,CORS_ALLOW_ORIGIN,MAILER_DSN,GOOGLE_RECAPTCHA_SECRET_KEY,GOOGLE_RECAPTCHA_SITE_KEY"
UNIQUE_ID 
"Z7nTUbiBoyj8JZ8-HGyF5gAAAAw"

Sub Requests 6

CookieController :: renderAnalysis (token = 250294)

Key Value
_controller 
"App\Controller\CookieController::renderAnalysis"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"1f5a3a"

AppController :: renderHeader (token = b332f1)

Key Value
_controller 
"App\Controller\AppController::renderHeader"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"0a18ab"
slug 
"home"

ArticleController :: trendingArticle (token = b04c5a)

Key Value
_controller 
"App\Controller\ArticleController::trendingArticle"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"28243b"
category 
"Science"

ArticleController :: relatedArticles (token = 58db33)

Key Value
_controller 
"App\Controller\ArticleController::relatedArticles"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"61e422"
current_article 
App\Entity\Article {#1094
  -id: 1418
  -title: "Digital Health Therapeutics Issues and Opportunities"
  -slug: "digital-health-therapeutics-issues-and-opportunities"
  -introtext: "<p>Digital health refers to using information and communications technologies to send or receive medical information. Some provide information and education while others have the intended use of diagnosing or treating a patient with symptoms or a disease. In the latter case, they can be considered a medical device , and, as such, what is more commonly being referred to as a digital therapeutic (DTx).</p>\r\n"
  -content: """
    \r\n
    <p>According to the digital therapeutics alliance,&nbsp;digital therapeutics represent a new generation of healthcare that uses innovative, clinically-validated disease management and direct treatment applications to enhance, and in some cases replace, current medical practices and treatments.</p>\r\n
    <p>DTx products demonstrate safety and efficacy in randomized clinical trials, receive regulatory clearance when used as a medical device, integrate into clinical practice, may be prescribed by healthcare providers, and tailor to patients’ clinical needs, goals, and lifestyles.</p>\r\n
    <p>Since this is an evolving technology in medical care, here are some things you should know:</p>\r\n
    <p>1.&nbsp;A medical device is defined within the Food Drug &amp; Cosmetic Act&nbsp;as "...an instrument, apparatus, implement, machine, contrivance, implant, in vitro reagent, or other similar or related article, including a component part, or accessory which is: recognized in the official National Formulary, or the United States Pharmacopoeia, or any supplement to them, intended for use in the diagnosis of disease or other conditions, or in the cure, mitigation, treatment, or prevention of disease, in man or other animals, or intended to affect the structure or any function of the body of man or other animals, and which does not achieve any of it's primary intended purposes through chemical action within or on the body of man or other animals and which is not dependent upon being metabolized for the achievement of any of its primary intended purposes."&nbsp;</p>\r\n
    <p>2.&nbsp;How the FDA is regulating digital health software and digital health therapeutics is constantly changing and evolving.</p>\r\n
    <p>3.&nbsp;There are innumerable applications and intended uses for digital health therapeutics</p>\r\n
    <p>4.&nbsp;Payers are deciding which digital health therapeutics warrant payment or reimbursement</p>\r\n
    <p>5.&nbsp;There are significant digital therapeutics IP issues.</p>\r\n
    <p>6. DTx raises myriad pre- and post-launch regulatory, privacy, security and promotional issues.&nbsp;</p>\r\n
    <p>7. There are significant barriers to&nbsp;DTx clinical translation, dissemination and implementation</p>\r\n
    <p>8. Medical schools and post-graduate training programs are not providing students and trainees with the knowledge, skills, abilities and competencies to assess and decide whether to prescribe DTx.</p>\r\n
    <p>9. Patients have low DTx IQs and many are unable to use them due to lack of access to affordable mobile technologies or broadband.</p>\r\n
    <p>10. There is an inadequate digital health clinical trials ecosystem. Digital health technologies are used to support and make more&nbsp;effective and efficient clinical trials.</p>\r\n
    <p>11. There is a convergence of medtech, DTx and biopharma complicating the IP, regulatory and reimbursement environment</p>\r\n
    <p>12.&nbsp;Capital sources are subsegmenting into various DTX applications and technologies</p>\r\n
    <p>DTx entrepreneurs are pushing the limits of new rules, regulations and commercialization pathways. Regulators and other stakeholders are playing catch up and , as such, are lagging indicators. Like all new therapeutic classes (think immuno-oncology, precision medicine or stem cell treatments) , it will take perhaps a generation or more for DTx applications to become the standard of care. Like other new treatments, most will fail. Consequently,we should subject them to a more rigorous cost-effective analysis so we don't make the same mistakes we've made with me-too drugs and devices that are now collecting dust in medicine cabinets and storage rooms.</p>\r\n
    <p>Arlen Meyers, MD, MBA is the President and CEO of the&nbsp;Society of Physician Entrepreneurs</p>
    """
  -user: Proxies\__CG__\App\Entity\User {#1092 …}
  -createdAt: DateTime @1522420546 {#1145
    date: 2018-03-30 14:35:46.0 UTC (+00:00)
  }
  -updatedAt: DateTime @1621358954 {#1150
    date: 2021-05-18 17:29:14.0 UTC (+00:00)
  }
  -deletedAt: null
  -category: App\Entity\Category {#445 …}
  -status: "published"
  -imageCard: Proxies\__CG__\App\Entity\File {#1184 …}
  -ImageHeader: Proxies\__CG__\App\Entity\File {#1184 …}
  -featured: false
  -mainView: false
  -clicks: 3296
  -comments: Doctrine\ORM\PersistentCollection {#1125 …}
  -reviewed_at: DateTime @1522420549 {#1148
    date: 2018-03-30 14:35:49.0 UTC (+00:00)
  }
  -metakey: ""
  -metadesc: "Digital health refers to using information and communications technologies to send or receive medical information. Some provide information and education while others have the intended use of diagnosing or treating a patient with symptoms or a disease. "
  -robots: null
  -publishedAt: DateTime @1522420549 {#1147
    date: 2018-03-30 14:35:49.0 UTC (+00:00)
  }
  -canonical: null
  -superTag: null
}

AppController :: renderFooter (token = 644c9a)

Key Value
_controller 
"App\Controller\AppController::renderFooter"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"94bac5"

CookieController :: renderCookie (token = 949d41)

Key Value
_controller 
"App\Controller\CookieController::renderCookie"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"b5ce1a"