GET https://rct.dev.bbntimes.com/science/the-neuroscience-of-depression

Response
200 OK
IP
3.145.81.198
Profiled on
Token
71f44f

ArticleController :: show

Request

GET Parameters

None

POST Parameters

None

Uploaded Files

None

Request Attributes

Key Value
_controller 
"App\Controller\ArticleController::show"
_firewall_context 
"security.firewall.map.context.main"
_links 
Symfony\Component\WebLink\GenericLinkProvider {#3587
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    3706 => Symfony\Component\WebLink\Link {#3706
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      -attributes: [
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    3705 => Symfony\Component\WebLink\Link {#3705
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      -rel: [
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      ]
      -attributes: [
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    3704 => Symfony\Component\WebLink\Link {#3704
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    3702 => Symfony\Component\WebLink\Link {#3702
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      -rel: [
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      ]
      -attributes: [
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    }
    3701 => Symfony\Component\WebLink\Link {#3701
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      -rel: [
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      ]
      -attributes: [
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      ]
    }
    3700 => Symfony\Component\WebLink\Link {#3700
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      -rel: [
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      ]
      -attributes: [
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    }
    3699 => Symfony\Component\WebLink\Link {#3699
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      -rel: [
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      ]
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      ]
    }
    3698 => Symfony\Component\WebLink\Link {#3698
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      ]
    }
    3697 => Symfony\Component\WebLink\Link {#3697
      -href: "/build/term-condition-css.css"
      -rel: [
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      -attributes: [
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      ]
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      -attributes: [
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    }
    3695 => Symfony\Component\WebLink\Link {#3695
      -href: "/build/comment-css.css"
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      -attributes: [
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}
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"article_show"
_route_params 
[
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]
_security_firewall_run 
"_security_main"
_stopwatch_token 
"b49bc9"
category 
"science"
slug 
"the-neuroscience-of-depression"

Request Headers

Header Value
accept 
"*/*"
accept-encoding 
"gzip, br, zstd, deflate"
connection 
"close"
cookie 
"PHPSESSID=9fooee0h9rc2h1s0e57h62kv80"
host 
"rct.dev.bbntimes.com"
user-agent 
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
x-php-ob-level 
"1"

Request Content

Request content not available (it was retrieved as a resource).

Response

Response Headers

Header Value
cache-control 
"no-cache, private"
content-type 
"text/html; charset=UTF-8"
date 
"Sat, 22 Feb 2025 08:30:49 GMT"
link 
"</build/runtime.js>; rel="preload"; as="script",</build/644.js>; rel="preload"; as="script",</build/502.js>; rel="preload"; as="script",</build/app.js>; rel="preload"; as="script",</build/view-more.js>; rel="preload"; as="script",</build/term-condition.js>; rel="preload"; as="script",</build/contact.js>; rel="preload"; as="script",</build/scroll-infinite-article.js>; rel="preload"; as="script",</build/app.css>; rel="preload"; as="style",</build/cookie-style.css>; rel="preload"; as="style",</build/term-condition-css.css>; rel="preload"; as="style",</build/contact-css.css>; rel="preload"; as="style",</build/comment-css.css>; rel="preload"; as="style""
x-debug-token 
"71f44f"

Cookies

Request Cookies

Key Value
PHPSESSID 
"9fooee0h9rc2h1s0e57h62kv80"

Response Cookies

No response cookies

Session 6

Session Metadata

Key Value
Created 
"Sat, 22 Feb 25 08:30:48 +0000"
Last used 
"Sat, 22 Feb 25 08:30:48 +0000"
Lifetime 
0

Session Attributes

Attribute Value
_csrf/https-comment 
"1D05CjnNzQ34HtCZiQX3CmpZEHD-7yKPtIhWMCCtmkM"
_csrf/https-cookie_accept 
"MA5LzExmrisPTjx2_XmMBAxvEyU61WY2ub90K2CULZM"

Session Usage

6 Usages
Stateless check enabled
Usage
Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:76
Show trace 
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:79
Show trace 
[
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:52
Show trace 
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  [
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:56
Show trace 
[
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    "type" => "->"
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    "line" => 76
    "function" => "handleRaw"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/Kernel.php"
    "line" => 197
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/runtime/Runner/Symfony/HttpKernelRunner.php"
    "line" => 35
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\Kernel"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    "line" => 29
    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
    "line" => 5
    "args" => [
      "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    ]
    "function" => "require_once"
  ]
]
Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage:41
Show trace 
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-core/Authentication/Token/Storage/UsageTrackingTokenStorage.php"
    "line" => 41
    "function" => "getMetadataBag"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
    "type" => "->"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/twig-bridge/AppVariable.php"
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    "function" => "getToken"
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    "function" => "twig_get_attribute"
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    "function" => "displayWithErrorHandling"
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    "line" => 379
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    "function" => "render"
    "class" => "Twig\Template"
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    "line" => 280
    "function" => "render"
    "class" => "Twig\TemplateWrapper"
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  [
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    "function" => "render"
    "class" => "Twig\Environment"
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    "line" => 453
    "function" => "doRenderView"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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    "function" => "doRender"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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  [
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    "function" => "render"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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    "function" => "renderHeader"
    "class" => "App\Controller\AppController"
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  [
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    "function" => "handleRaw"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpCache/SubRequestHandler.php"
    "line" => 86
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/Fragment/InlineFragmentRenderer.php"
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    "function" => "render"
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  [
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    "function" => "render"
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  [
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    "function" => "display"
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    "line" => 394
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/twig/twig/src/Template.php"
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    "function" => "displayWithErrorHandling"
    "class" => "Twig\Template"
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  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/twig/twig/src/Template.php"
    "line" => 379
    "function" => "display"
    "class" => "Twig\Template"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/twig/twig/src/TemplateWrapper.php"
    "line" => 38
    "function" => "render"
    "class" => "Twig\Template"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/twig/twig/src/Environment.php"
    "line" => 280
    "function" => "render"
    "class" => "Twig\TemplateWrapper"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/framework-bundle/Controller/AbstractController.php"
    "line" => 448
    "function" => "render"
    "class" => "Twig\Environment"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/framework-bundle/Controller/AbstractController.php"
    "line" => 453
    "function" => "doRenderView"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/framework-bundle/Controller/AbstractController.php"
    "line" => 253
    "function" => "doRender"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/src/Controller/ArticleController.php"
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    "function" => "render"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 181
    "function" => "show"
    "class" => "App\Controller\ArticleController"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 76
    "function" => "handleRaw"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
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  [
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    "line" => 197
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/runtime/Runner/Symfony/HttpKernelRunner.php"
    "line" => 35
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\Kernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    "line" => 29
    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
    "line" => 5
    "args" => [
      "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    ]
    "function" => "require_once"
  ]
]
Symfony\Component\Security\Http\Firewall\ContextListener:171
Show trace 
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-http/Firewall/ContextListener.php"
    "line" => 171
    "function" => "remove"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/Debug/WrappedListener.php"
    "line" => 116
    "function" => "onKernelResponse"
    "class" => "Symfony\Component\Security\Http\Firewall\ContextListener"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/EventDispatcher.php"
    "line" => 220
    "function" => "__invoke"
    "class" => "Symfony\Component\EventDispatcher\Debug\WrappedListener"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/EventDispatcher.php"
    "line" => 56
    "function" => "callListeners"
    "class" => "Symfony\Component\EventDispatcher\EventDispatcher"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/Debug/TraceableEventDispatcher.php"
    "line" => 139
    "function" => "dispatch"
    "class" => "Symfony\Component\EventDispatcher\EventDispatcher"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 214
    "function" => "dispatch"
    "class" => "Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 202
    "function" => "filterResponse"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 76
    "function" => "handleRaw"
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    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/Kernel.php"
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    "function" => "handle"
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    "function" => "handle"
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    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
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    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
    "type" => "->"
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  [
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    "args" => [
      "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
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    "function" => "require_once"
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]

Flashes

Flashes

No flash messages were created.

Server Parameters

Server Parameters

Defined in .env

Key Value
APP_ENV 
"dev"
APP_SECRET 
"0a988e63f011514eaabfc650b599af4d"
CORS_ALLOW_ORIGIN 
"*"
DATABASE_URL 
"mysql://bbndb_rctuser:33F5W25z40or0f7@localhost:3306/rct_bbntimes"
GOOGLE_RECAPTCHA_SECRET_KEY 
"6LdV5fgpAAAAANxzTG8ZMfIjil1wu-1vrQvnUt-x"
GOOGLE_RECAPTCHA_SITE_KEY 
"6LdV5fgpAAAAAENKcn73MJAhQrbtQeqgyC4wDLMP"
MAILER_DSN 
"smtp://no-reply%40rct.dev.bbntimes.com:Bl6%26gLD48%26Of919@rct.dev.bbntimes.com:465"
MARIADB_PASSWORD 
"i!87pK&!85ezc8"

Defined as regular env variables

Key Value
APP_DEBUG 
"1"
BASE 
"/public"
CONTEXT_DOCUMENT_ROOT 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
CONTEXT_PREFIX 
""
DOCUMENT_ROOT 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
FCGI_ROLE 
"RESPONDER"
GATEWAY_INTERFACE 
"CGI/1.1"
HTTPS 
"on"
HTTP_ACCEPT 
"*/*"
HTTP_ACCEPT_ENCODING 
"gzip, br, zstd, deflate"
HTTP_CONNECTION 
"close"
HTTP_COOKIE 
"PHPSESSID=9fooee0h9rc2h1s0e57h62kv80"
HTTP_HOST 
"rct.dev.bbntimes.com"
HTTP_USER_AGENT 
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
PATH 
"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/sbin:/bin:/snap/bin"
PHP_SELF 
"/public/index.php"
PP_CUSTOM_PHP_CGI_INDEX 
"plesk-php81-fastcgi"
PP_CUSTOM_PHP_INI 
"/var/www/vhosts/system/rct.dev.bbntimes.com/etc/php.ini"
QUERY_STRING 
""
REDIRECT_BASE 
"/public"
REDIRECT_HTTPS 
"on"
REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_HTTPS 
"on"
REDIRECT_REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/the-neuroscience-of-depression"
REDIRECT_REDIRECT_SCRIPT_URL 
"/science/the-neuroscience-of-depression"
REDIRECT_REDIRECT_SSL_TLS_SNI 
"rct.dev.bbntimes.com"
REDIRECT_REDIRECT_STATUS 
"200"
REDIRECT_REDIRECT_UNIQUE_ID 
"Z7mLOZDyWLT8YV1VjBo2EgAAAIU"
REDIRECT_SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/the-neuroscience-of-depression"
REDIRECT_SCRIPT_URL 
"/science/the-neuroscience-of-depression"
REDIRECT_SSL_TLS_SNI 
"rct.dev.bbntimes.com"
REDIRECT_STATUS 
"200"
REDIRECT_UNIQUE_ID 
"Z7mLOZDyWLT8YV1VjBo2EgAAAIU"
REDIRECT_URL 
"/public/science/the-neuroscience-of-depression"
REMOTE_ADDR 
"3.145.81.198"
REMOTE_PORT 
"59445"
REQUEST_METHOD 
"GET"
REQUEST_SCHEME 
"https"
REQUEST_TIME 
1740213049
REQUEST_TIME_FLOAT 
1740213049.4319
REQUEST_URI 
"/science/the-neuroscience-of-depression"
SCRIPT_FILENAME 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
SCRIPT_NAME 
"/public/index.php"
SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/the-neuroscience-of-depression"
SCRIPT_URL 
"/science/the-neuroscience-of-depression"
SERVER_ADDR 
"5.196.1.209"
SERVER_ADMIN 
"[no address given]"
SERVER_NAME 
"rct.dev.bbntimes.com"
SERVER_PORT 
"443"
SERVER_PROTOCOL 
"HTTP/1.1"
SERVER_SIGNATURE 
"<address>Apache Server at rct.dev.bbntimes.com Port 443</address>\n"
SERVER_SOFTWARE 
"Apache"
SSL_TLS_SNI 
"rct.dev.bbntimes.com"
SYMFONY_DOTENV_VARS 
"APP_ENV,APP_SECRET,DATABASE_URL,MARIADB_PASSWORD,CORS_ALLOW_ORIGIN,MAILER_DSN,GOOGLE_RECAPTCHA_SECRET_KEY,GOOGLE_RECAPTCHA_SITE_KEY"
UNIQUE_ID 
"Z7mLOZDyWLT8YV1VjBo2EgAAAIU"

Sub Requests 6

CookieController :: renderAnalysis (token = 7084ad)

Key Value
_controller 
"App\Controller\CookieController::renderAnalysis"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"66b053"

AppController :: renderHeader (token = e12d65)

Key Value
_controller 
"App\Controller\AppController::renderHeader"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"7a0c9b"
slug 
"home"

ArticleController :: trendingArticle (token = 0dd5d7)

Key Value
_controller 
"App\Controller\ArticleController::trendingArticle"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"2bcbf5"
category 
"Science"

ArticleController :: relatedArticles (token = 881f1d)

Key Value
_controller 
"App\Controller\ArticleController::relatedArticles"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"5c1bd2"
current_article 
App\Entity\Article {#1094
  -id: 13512
  -title: "The Neuroscience of Depression "
  -slug: "the-neuroscience-of-depression"
  -introtext: "<p>Depression is a mental health disorder that affects millions of people around the world.</p>\r\n"
  -content: """
    \r\n
    <p>It is characterized by feelings of sadness, hopelessness, and a lack of energy and motivation. While depression is a well-known condition, its underlying causes are still not fully understood.</p>\r\n
    <p><a href="science/the-neuroscience-of-artificial-intelligence" target="_blank" rel="noopener">Recent advancements in neuroscience </a>have begun to shed light on the biological and physiological mechanisms involved in depression, offering new opportunities for the development of effective treatments. In this article, we will explore the latest research on the neuroscience of depression and its implications for the treatment of this debilitating condition.</p>\r\n
    <h2>1. The Role of Neurotransmitters</h2>\r\n
    <p><img src="/images/Causes-Of-Neurotransmitter-Imbalance-1-scaled.jpg.optimal.jpg" alt="Causes-Of-Neurotransmitter-Imbalance-1-scaled.jpg.optimal.jpg" width="722" height="722" /></p>\r\n
    <p>&nbsp;</p>\r\n
    <p><em><a href="https://www.xcode.life/genes-and-health/what-neurotransmitter-causes-depression/" target="_blank" rel="noopener">Source: XCode Life</a></em></p>\r\n
    <p>One of the key areas of research in the neuroscience of depression is the role of neurotransmitters, chemical messengers in the brain that play a crucial role in regulating mood and emotion. Imbalances in the levels of certain neurotransmitters, such as serotonin and norepinephrine, have been associated with depression.</p>\r\n
    <p>For example, the widely used class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) work by increasing the levels of serotonin in the brain, helping to alleviate the symptoms of depression.</p>\r\n
    <h2>2. Brain Structure in Depression</h2>\r\n
    <p><img src="/images/Study-shows-brain-structure-changes-during-depression.jpg" alt="Study-shows-brain-structure-changes-during-depression.jpg" width="722" height="480" /></p>\r\n
    <p><em><a href="https://www.upi.com/Health_News/2017/03/07/Study-shows-brain-structure-changes-during-depression/4951488892582/" target="_blank" rel="noopener">Source: UPI</a></em></p>\r\n
    <p>Another area of interest in the neuroscience of depression is the brain structure of individuals with the disorder. Using imaging techniques such as magnetic resonance imaging (MRI), researchers have been able to examine the brain structure of individuals with depression and compare it to healthy individuals.</p>\r\n
    <p>Studies have shown that individuals with depression tend to have a smaller hippocampus, a region of the brain involved in regulating emotions and memory. In addition, they have shown changes in the activity levels of the amygdala, a region involved in processing emotions such as fear and anxiety.</p>\r\n
    <p>These findings suggest that structural changes in the brain may play a role in the development of depression, and could offer new targets for the development of treatments.</p>\r\n
    <h2>3. Genetics of Depression</h2>\r\n
    <p><img src="/images/Genetics_of_Depression.png" alt="Genetics_of_Depression.png" /></p>\r\n
    <p><a href="https://www.nature.com/articles/s41398-019-0450-5" target="_blank" rel="noopener"><em>Source: Nature Magazine</em></a></p>\r\n
    <p>While the causes of depression are complex and involve a combination of biological, environmental, and psychological factors, a growing body of research suggests that genetics also play a role. Studies have shown that depression tends to run in families, suggesting a genetic component.</p>\r\n
    <p>More recently, the use of genome-wide association studies (GWAS) has allowed researchers to identify specific genes associated with depression. For example, a study published in 2018 identified over 20 genes that are associated with depression, offering new insights into the underlying causes of the disorder.</p>\r\n
    <p>These findings have important implications for the development of personalized treatments for depression, allowing healthcare providers to tailor treatments to the specific genetic profile of each individual.</p>\r\n
    <h2>4. The Impact of Environmental Factors in Depression</h2>\r\n
    <p><img src="/images/The_Impact_of_Environmental_Factors_in_Depression.jpg" alt="The_Impact_of_Environmental_Factors_in_Depression.jpg" /></p>\r\n
    <p>&nbsp;</p>\r\n
    <p><a href="https://www.sciencedirect.com/science/article/abs/pii/S0190740920311518" target="_blank" rel="noopener">Source: Science Direct</a><br /><br /></p>\r\n
    <p>While biology and genetics are important factors in the development of depression, environmental factors such as stress and trauma also play a significant role. Traumatic events such as abuse, neglect, or loss can trigger depression in vulnerable individuals.</p>\r\n
    <p>In addition, chronic stress has been shown to alter brain structure and function, potentially contributing to the development of depression. For example, a study published in 2016 showed that chronic stress led to changes in the size and activity levels of the hippocampus, a region of the brain involved in regulating emotions and memory.</p>\r\n
    <p>These findings suggest that addressing environmental factors such as stress and trauma may be an important component of the treatment of depression.</p>\r\n
    <h2>Conclusion</h2>\r\n
    <p>The field of neuroscience has made significant progress in understanding the causes of depression and its underlying biological mechanisms. From the role of neurotransmitters and brain structure to the impact of genetics and environmental factors, the latest research is offering new opportunities for the development of effective treatments for this debilitating condition.</p>\r\n
    <p>While much work remains to be done, these advancements offer hope for individuals struggling with depression and their families</p>
    """
  -user: Proxies\__CG__\App\Entity\User {#1092 …}
  -createdAt: DateTime @1675685837 {#1145
    date: 2023-02-06 12:17:17.0 UTC (+00:00)
  }
  -updatedAt: DateTime @1675685955 {#1150
    date: 2023-02-06 12:19:15.0 UTC (+00:00)
  }
  -deletedAt: null
  -category: App\Entity\Category {#445 …}
  -status: "published"
  -imageCard: Proxies\__CG__\App\Entity\File {#1184 …}
  -ImageHeader: Proxies\__CG__\App\Entity\File {#1184 …}
  -featured: false
  -mainView: false
  -clicks: 2545
  -comments: Doctrine\ORM\PersistentCollection {#1125 …}
  -reviewed_at: DateTime @1675685837 {#1148
    date: 2023-02-06 12:17:17.0 UTC (+00:00)
  }
  -metakey: "The Neuroscience of Depression"
  -metadesc: "Depression is a mental health disorder that affects millions of people around the world."
  -robots: null
  -publishedAt: DateTime @1675685837 {#1147
    date: 2023-02-06 12:17:17.0 UTC (+00:00)
  }
  -canonical: null
  -superTag: null
}

AppController :: renderFooter (token = be941b)

Key Value
_controller 
"App\Controller\AppController::renderFooter"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"ebfdca"

CookieController :: renderCookie (token = db7e90)

Key Value
_controller 
"App\Controller\CookieController::renderCookie"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"dca196"