GET https://rct.dev.bbntimes.com/science/nobel-laureate-frances-h-arnold-s-innovative-discovery

Response
200 OK
IP
18.216.131.64
Profiled on
Token
bf9dce

ArticleController :: show

Request

GET Parameters

None

POST Parameters

None

Uploaded Files

None

Request Attributes

Key Value
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"App\Controller\ArticleController::show"
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"security.firewall.map.context.main"
_links 
Symfony\Component\WebLink\GenericLinkProvider {#3649
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    3762 => Symfony\Component\WebLink\Link {#3762
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    3757 => Symfony\Component\WebLink\Link {#3757
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"article_show"
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[
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]
_security_firewall_run 
"_security_main"
_stopwatch_token 
"cb8090"
category 
"science"
slug 
"nobel-laureate-frances-h-arnold-s-innovative-discovery"

Request Headers

Header Value
accept 
"*/*"
accept-encoding 
"gzip, br, zstd, deflate"
connection 
"close"
cookie 
"PHPSESSID=71cre37lo4b22qlkhlvu3j84lr"
host 
"rct.dev.bbntimes.com"
user-agent 
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
x-php-ob-level 
"1"

Request Content

Request content not available (it was retrieved as a resource).

Response

Response Headers

Header Value
cache-control 
"no-cache, private"
content-type 
"text/html; charset=UTF-8"
date 
"Sat, 22 Feb 2025 13:34:52 GMT"
link 
"</build/runtime.js>; rel="preload"; as="script",</build/644.js>; rel="preload"; as="script",</build/502.js>; rel="preload"; as="script",</build/app.js>; rel="preload"; as="script",</build/view-more.js>; rel="preload"; as="script",</build/term-condition.js>; rel="preload"; as="script",</build/contact.js>; rel="preload"; as="script",</build/scroll-infinite-article.js>; rel="preload"; as="script",</build/app.css>; rel="preload"; as="style",</build/cookie-style.css>; rel="preload"; as="style",</build/term-condition-css.css>; rel="preload"; as="style",</build/contact-css.css>; rel="preload"; as="style",</build/comment-css.css>; rel="preload"; as="style""
x-debug-token 
"bf9dce"

Cookies

Request Cookies

Key Value
PHPSESSID 
"71cre37lo4b22qlkhlvu3j84lr"

Response Cookies

No response cookies

Session 6

Session Metadata

Key Value
Created 
"Sat, 22 Feb 25 13:34:30 +0000"
Last used 
"Sat, 22 Feb 25 13:34:50 +0000"
Lifetime 
0

Session Attributes

Attribute Value
_csrf/https-comment 
"Sycp2XHelnQbO0H0-xJFBKDrCP8_rVcXuYowDVDUKiQ"
_csrf/https-cookie_accept 
"7NoLIutHpcd_p--AUmLoeU0Uq9dAASuz3nPBmjg9JR8"

Session Usage

6 Usages
Stateless check enabled
Usage
Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:76
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:79
Show trace 
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:52
Show trace 
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Symfony\Component\Security\Csrf\TokenStorage\SessionTokenStorage:56
Show trace 
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    "function" => "show"
    "class" => "App\Controller\ArticleController"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 76
    "function" => "handleRaw"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/Kernel.php"
    "line" => 197
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/runtime/Runner/Symfony/HttpKernelRunner.php"
    "line" => 35
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\Kernel"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    "line" => 29
    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
    "line" => 5
    "args" => [
      "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    ]
    "function" => "require_once"
  ]
]
Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage:41
Show trace 
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-core/Authentication/Token/Storage/UsageTrackingTokenStorage.php"
    "line" => 41
    "function" => "getMetadataBag"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/twig-bridge/AppVariable.php"
    "line" => 103
    "function" => "getToken"
    "class" => "Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/twig/twig/src/Extension/CoreExtension.php"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/var/cache/dev/twig/a4/a456f2f504a18cd81037fa69e543310c.php"
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    "function" => "twig_get_attribute"
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    "function" => "displayWithErrorHandling"
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    "function" => "render"
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    "function" => "render"
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    "line" => 453
    "function" => "doRenderView"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/framework-bundle/Controller/AbstractController.php"
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    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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    "function" => "render"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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    "function" => "renderHeader"
    "class" => "App\Controller\AppController"
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    "line" => 76
    "function" => "handleRaw"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpCache/SubRequestHandler.php"
    "line" => 86
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/Fragment/InlineFragmentRenderer.php"
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    "function" => "render"
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    "class" => "Symfony\Component\HttpKernel\DependencyInjection\LazyLoadingFragmentHandler"
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    "function" => "displayBlock"
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    "function" => "displayWithErrorHandling"
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    "line" => 379
    "function" => "display"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/twig/twig/src/TemplateWrapper.php"
    "line" => 38
    "function" => "render"
    "class" => "Twig\Template"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/twig/twig/src/Environment.php"
    "line" => 280
    "function" => "render"
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    "function" => "render"
    "class" => "Twig\Environment"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/framework-bundle/Controller/AbstractController.php"
    "line" => 453
    "function" => "doRenderView"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
    "type" => "->"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/framework-bundle/Controller/AbstractController.php"
    "line" => 253
    "function" => "doRender"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/src/Controller/ArticleController.php"
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    "function" => "render"
    "class" => "Symfony\Bundle\FrameworkBundle\Controller\AbstractController"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 181
    "function" => "show"
    "class" => "App\Controller\ArticleController"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 76
    "function" => "handleRaw"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/Kernel.php"
    "line" => 197
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/runtime/Runner/Symfony/HttpKernelRunner.php"
    "line" => 35
    "function" => "handle"
    "class" => "Symfony\Component\HttpKernel\Kernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    "line" => 29
    "function" => "run"
    "class" => "Symfony\Component\Runtime\Runner\Symfony\HttpKernelRunner"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
    "line" => 5
    "args" => [
      "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
    ]
    "function" => "require_once"
  ]
]
Symfony\Component\Security\Http\Firewall\ContextListener:171
Show trace 
[
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/security-http/Firewall/ContextListener.php"
    "line" => 171
    "function" => "remove"
    "class" => "Symfony\Component\HttpFoundation\Session\Session"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/Debug/WrappedListener.php"
    "line" => 116
    "function" => "onKernelResponse"
    "class" => "Symfony\Component\Security\Http\Firewall\ContextListener"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/EventDispatcher.php"
    "line" => 220
    "function" => "__invoke"
    "class" => "Symfony\Component\EventDispatcher\Debug\WrappedListener"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/EventDispatcher.php"
    "line" => 56
    "function" => "callListeners"
    "class" => "Symfony\Component\EventDispatcher\EventDispatcher"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/event-dispatcher/Debug/TraceableEventDispatcher.php"
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    "function" => "dispatch"
    "class" => "Symfony\Component\EventDispatcher\EventDispatcher"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 214
    "function" => "dispatch"
    "class" => "Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher"
    "type" => "->"
  ]
  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
    "line" => 202
    "function" => "filterResponse"
    "class" => "Symfony\Component\HttpKernel\HttpKernel"
    "type" => "->"
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  [
    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/symfony/http-kernel/HttpKernel.php"
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    "function" => "handleRaw"
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    "function" => "handle"
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    "file" => "/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/vendor/autoload_runtime.php"
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]

Flashes

Flashes

No flash messages were created.

Server Parameters

Server Parameters

Defined in .env

Key Value
APP_ENV 
"dev"
APP_SECRET 
"0a988e63f011514eaabfc650b599af4d"
CORS_ALLOW_ORIGIN 
"*"
DATABASE_URL 
"mysql://bbndb_rctuser:33F5W25z40or0f7@localhost:3306/rct_bbntimes"
GOOGLE_RECAPTCHA_SECRET_KEY 
"6LdV5fgpAAAAANxzTG8ZMfIjil1wu-1vrQvnUt-x"
GOOGLE_RECAPTCHA_SITE_KEY 
"6LdV5fgpAAAAAENKcn73MJAhQrbtQeqgyC4wDLMP"
MAILER_DSN 
"smtp://no-reply%40rct.dev.bbntimes.com:Bl6%26gLD48%26Of919@rct.dev.bbntimes.com:465"
MARIADB_PASSWORD 
"i!87pK&!85ezc8"

Defined as regular env variables

Key Value
APP_DEBUG 
"1"
BASE 
"/public"
CONTEXT_DOCUMENT_ROOT 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
CONTEXT_PREFIX 
""
DOCUMENT_ROOT 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com"
FCGI_ROLE 
"RESPONDER"
GATEWAY_INTERFACE 
"CGI/1.1"
HTTPS 
"on"
HTTP_ACCEPT 
"*/*"
HTTP_ACCEPT_ENCODING 
"gzip, br, zstd, deflate"
HTTP_CONNECTION 
"close"
HTTP_COOKIE 
"PHPSESSID=71cre37lo4b22qlkhlvu3j84lr"
HTTP_HOST 
"rct.dev.bbntimes.com"
HTTP_USER_AGENT 
"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
PATH 
"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/sbin:/bin:/snap/bin"
PHP_SELF 
"/public/index.php"
PP_CUSTOM_PHP_CGI_INDEX 
"plesk-php81-fastcgi"
PP_CUSTOM_PHP_INI 
"/var/www/vhosts/system/rct.dev.bbntimes.com/etc/php.ini"
QUERY_STRING 
""
REDIRECT_BASE 
"/public"
REDIRECT_HTTPS 
"on"
REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_HTTPS 
"on"
REDIRECT_REDIRECT_PASSENGER_COMPILE_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_PASSENGER_DOWNLOAD_NATIVE_SUPPORT_BINARY 
"0"
REDIRECT_REDIRECT_SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/nobel-laureate-frances-h-arnold-s-innovative-discovery"
REDIRECT_REDIRECT_SCRIPT_URL 
"/science/nobel-laureate-frances-h-arnold-s-innovative-discovery"
REDIRECT_REDIRECT_SSL_TLS_SNI 
"rct.dev.bbntimes.com"
REDIRECT_REDIRECT_STATUS 
"200"
REDIRECT_REDIRECT_UNIQUE_ID 
"Z7nSe5DyWLT8YV1VjBpW1gAAAI0"
REDIRECT_SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/nobel-laureate-frances-h-arnold-s-innovative-discovery"
REDIRECT_SCRIPT_URL 
"/science/nobel-laureate-frances-h-arnold-s-innovative-discovery"
REDIRECT_SSL_TLS_SNI 
"rct.dev.bbntimes.com"
REDIRECT_STATUS 
"200"
REDIRECT_UNIQUE_ID 
"Z7nSe5DyWLT8YV1VjBpW1gAAAI0"
REDIRECT_URL 
"/public/science/nobel-laureate-frances-h-arnold-s-innovative-discovery"
REMOTE_ADDR 
"18.216.131.64"
REMOTE_PORT 
"22453"
REQUEST_METHOD 
"GET"
REQUEST_SCHEME 
"https"
REQUEST_TIME 
1740231291
REQUEST_TIME_FLOAT 
1740231291.7956
REQUEST_URI 
"/science/nobel-laureate-frances-h-arnold-s-innovative-discovery"
SCRIPT_FILENAME 
"/var/www/vhosts/dev.bbntimes.com/rct.dev.bbntimes.com/public/index.php"
SCRIPT_NAME 
"/public/index.php"
SCRIPT_URI 
"https://rct.dev.bbntimes.com/science/nobel-laureate-frances-h-arnold-s-innovative-discovery"
SCRIPT_URL 
"/science/nobel-laureate-frances-h-arnold-s-innovative-discovery"
SERVER_ADDR 
"5.196.1.209"
SERVER_ADMIN 
"[no address given]"
SERVER_NAME 
"rct.dev.bbntimes.com"
SERVER_PORT 
"443"
SERVER_PROTOCOL 
"HTTP/1.1"
SERVER_SIGNATURE 
"<address>Apache Server at rct.dev.bbntimes.com Port 443</address>\n"
SERVER_SOFTWARE 
"Apache"
SSL_TLS_SNI 
"rct.dev.bbntimes.com"
SYMFONY_DOTENV_VARS 
"APP_ENV,APP_SECRET,DATABASE_URL,MARIADB_PASSWORD,CORS_ALLOW_ORIGIN,MAILER_DSN,GOOGLE_RECAPTCHA_SECRET_KEY,GOOGLE_RECAPTCHA_SITE_KEY"
UNIQUE_ID 
"Z7nSe5DyWLT8YV1VjBpW1gAAAI0"

Sub Requests 6

CookieController :: renderAnalysis (token = a3d512)

Key Value
_controller 
"App\Controller\CookieController::renderAnalysis"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"ed0035"

AppController :: renderHeader (token = ff931a)

Key Value
_controller 
"App\Controller\AppController::renderHeader"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"48371e"
slug 
"home"

ArticleController :: trendingArticle (token = b07fcd)

Key Value
_controller 
"App\Controller\ArticleController::trendingArticle"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"8f1d2d"
category 
"Science"

ArticleController :: relatedArticles (token = 2010e4)

Key Value
_controller 
"App\Controller\ArticleController::relatedArticles"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"c6987e"
current_article 
App\Entity\Article {#1094
  -id: 2931
  -title: "Nobel Laureate Frances H. Arnold’s Innovative Discovery"
  -slug: "nobel-laureate-frances-h-arnold-s-innovative-discovery"
  -introtext: "<p>Directed evolution (DE) is the acceleration of natural evolution using an iterative laboratory processes at the molecular level. Directed evolution of enzymes and binding proteins was a concept that was theorized in by German biophysicist Manfred Eigen — a Nobel Prize in Chemistry laureate, who was awarded the prize in 1967 for his research on fast chemical reactions.</p>\r\n"
  -content: """
    \r\n
    <p>In Eigen theory, published in 1984, he predicted that an “evolutionary machine” would one day be able to produce optimized enzymes. Nearly a decade later, Eigen’s theory became a reality through the innovative research of American Frances H. Arnold — the first woman to win the 2016 Millennium Technology Prize, and the first woman to win the Nobel Prize in Chemistry in 2018.</p>\r\n
    <p>In 1993, Frances H. Arnold, a California Institute of Technology (Caltech) professor, chemical engineer, and prolific inventor, was the first person in the world to have successfully implemented the directed evolution of enzymes. Enzymes are biological catalysts that accelerate chemical reactions. Most enzymes are proteins, with the exception of ribozymes, an RNA molecule with enzymatic activity. For example, salivary amylase is the enzyme present in human saliva that aids in digestion by breaking down starches into simple sugars. In addition to digestion of food, enzymes catalyzes cell metabolism in the body. Commercially enzymes are used for a wide range of purposes, including medicine, food and beverage production, stain removal, meat tenderizer, and detergents.</p>\r\n
    <p>The enzyme that Arnold used in her breakthrough research was a protein-digesting enzyme called subtilisin E. Through laboratory techniques, Arnold directed the evolution of subtilisin E to a variant that was active in highly denaturing environment that had high concentrations of a polar organic solvent, dimethylformamide (DMF). &nbsp;In other words, Arnold discovered a method to speed up and direct the mutations of subtilisin E so that it could withstand higher concentrations of DMF — this was a watershed discovery.</p>\r\n
    <p>As a result of her innovative research, the Royal Swedish Academy of Sciences awarded Arnold the Nobel Prize for Chemistry 2018 (the other half of the prize was awarded to George P. Smith and Sir Gregory P. Winter for their work on phage display of peptides and antibodies).</p>\r\n
    <p>Arnold’s pioneering work opened an entirely new field that can be applied to solve real-world challenges in biotech, life sciences, chemical, consumer product goods, food, textiles, pharmaceutical and more industries. Frances H. Arnold has opened a world of possibilities through her scientific discovery, and it may help solve some of humanity’s greatest challenges through applied science in the future.<br /><br /></p>\r\n
    <p class="quote-left">Biology is very clever, and many solutions to important problems can be found by engineering it.</p>\r\n
    <p class="quote-right">Frances Arnold</p>\r\n
    <p><em>Copyright © 2018 Cami Rosso All rights reserved.</em></p>\r\n
    <h2><strong>References</strong></h2>\r\n
    <p>The Royal Swedish Academy of Sciences.”Scientific Background on the Nobel Prize in Chemistry 2018 — Directed Evolution of Enzymes and Binding Proteins.” 3 October 2018. Retrieved 11-1-2018 from&nbsp;<a href="https://old.nobelprize.org/che-sci.pdf?_ga=2.228216788.850160180.1538560699-1556534510.1538560699" target="_blank" rel="nofollow noopener">https://old.nobelprize.org/che-sci.pdf?_ga=2.228216788.850160180.1538560699-1556534510.1538560699</a></p>\r\n
    <p>Köste, Vera. “Interview with Frances H. Arnold — Design by Evolution.” ChemViews. 05 December 2011. Retrieved 11-1-2018 from <a href="https://www.chemistryviews.org/details/ezine/1376211/Interview_with_Frances_H__Arnold__Design_by_Evolution.html">https://www.chemistryviews.org/details/ezine/1376211/Interview_with_Frances_H__Arnold__Design_by_Evolution.html</a></p>\r\n
    <p>Golgowski, Nina. “Frances Arnold Becomes First American Woman to Win Nobel Prize in Chemistry.”&nbsp;<em>HuffPost</em>. 10/3/2018.</p>\r\n
    <p>Encyclopedia Britannica. “Manfred Eigen.” Retrieved 11-1-2018 from <a href="https://www.britannica.com/biography/Manfred-Eigen">https://www.britannica.com/biography/Manfred-Eigen</a></p>\r\n
    <p>Sansom, Clare.”When is an enzyme not a protein?”&nbsp;<em>Chemistry World</em>. 29 February 2016.</p>
    """
  -user: Proxies\__CG__\App\Entity\User {#1092 …}
  -createdAt: DateTime @1541146227 {#1145
    date: 2018-11-02 08:10:27.0 UTC (+00:00)
  }
  -updatedAt: DateTime @1541146539 {#1150
    date: 2018-11-02 08:15:39.0 UTC (+00:00)
  }
  -deletedAt: null
  -category: App\Entity\Category {#445 …}
  -status: "published"
  -imageCard: Proxies\__CG__\App\Entity\File {#1184 …}
  -ImageHeader: Proxies\__CG__\App\Entity\File {#1184 …}
  -featured: false
  -mainView: false
  -clicks: 4350
  -comments: Doctrine\ORM\PersistentCollection {#1125 …}
  -reviewed_at: DateTime @1541146225 {#1148
    date: 2018-11-02 08:10:25.0 UTC (+00:00)
  }
  -metakey: ""
  -metadesc: "Directed evolution (DE) is the acceleration of natural evolution using an iterative laboratory processes at the molecular level. Directed evolution of enzymes and binding proteins was a concept that was theorized in by German biophysicist Manfred Eigen — a Nobel Prize in Chemistry laureate, who was awarded the prize in 1967 for his research on fast chemical reactions."
  -robots: null
  -publishedAt: DateTime @1541146225 {#1147
    date: 2018-11-02 08:10:25.0 UTC (+00:00)
  }
  -canonical: null
  -superTag: null
}

AppController :: renderFooter (token = d23c59)

Key Value
_controller 
"App\Controller\AppController::renderFooter"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"b9aae3"

CookieController :: renderCookie (token = 52929d)

Key Value
_controller 
"App\Controller\CookieController::renderCookie"
_format 
"html"
_locale 
"en"
_stopwatch_token 
"269e83"